Aldehyde-Induced DNA and Protein Adducts as Biomarker Tools for Alcohol Use Disorder
نویسندگان
چکیده
منابع مشابه
Aldehyde-protein adducts in the liver as a result of ethanol-induced oxidative stress.
A number of systems that generate oxygen free radicals and reactive aldehydic species are activated by excessive ethanol consumption. Recent studies from human alcoholics and from experimental animals have indicated that acetaldehyde and aldehydic products of lipid peroxidation, which are generated in such processes, can bind to proteins forming stable adducts. Adduct formation may lead to seve...
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ژورنال
عنوان ژورنال: Trends in Molecular Medicine
سال: 2018
ISSN: 1471-4914
DOI: 10.1016/j.molmed.2017.12.003